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The present invention provides enzymes that have been optimized by implementation of Protein Repair One Stop Shop (PROSS), an algorithm that generates.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source rabbit LD skin > 2gm/kg (2000mg/kg) Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Rat LC inhalation > 5gm/m3/4H (5000mg/m3) Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Rat LD oral > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: 'HYPERMOTILITY, DIARRHEA' Acute Toxicity Data. Journal of the American College of Toxicology, Part B.

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